Ionis Pharmaceuticals (IONS) Financial Analysis & Valuation | Quarter Chart

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis... more
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. T... more

Company facts

Reported company information and share structure.

Company Share structure
Market Cap$9.01BExchangeNASDAQ
SectorHealthcareIndustryBiotechnology
CountryUSCEOBrett Monia
IPO Date1991-05-17CAGR19.23%
Employees1,480Websitewww.ionispharma.com
Div. YieldPayout Ratio
Buy Back YieldTotal Yield
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Key metrics

Reported fundamentals and market-derived technical indicators.

Fundamentals Technicals
EV$14.66BP/E-31.52Forward P/E-48.74PEG
P/S164.35P/B326.68P/CF-289.5P/FCF-257.23
Sales$873.76MSales 1Y-7.45%Sales 3Y38.56%Sales 5Y27.05%
EPS$-1.72EPS 1Y86.02%EPS 3Y60.19%EPS 5Y-10.36%
Sales QoQ8.88%EPS QoQ23.21%Sales QoQ Avg-1.42%EPS QoQ Avg-44.62%
Gross Margin98.16%Operating Margin-68.09%Profit Margin-64.64%ROCE-22.21%
ROA-19%ROE-111%Altman Z Score1.42Piotroski Score2
Current Ratio7.89Quick Ratio7.73Cash Ratio1.11Op. CF Ratio1.79
Debt/Equity3.67Debt/Assets0.54Lt Debt/Equity4.27Lt Debt/Cap.0.79
Intrst Cov.-9.48Inventory Turnover0.32Asset Turnover0.29Receivables Turnover14.85
Enterprise Value$14.66BP/E Ratio-31.52
Forward P/E-48.74PEG Ratio
P/S Ratio164.35P/B Ratio326.68
P/CF Ratio-289.5P/FCF Ratio-257.23
EPS$-1.72EPS Growth 1Y86.02%
EPS Growth 3Y60.19%EPS Growth 5Y-10.36%
Revenue Growth 1Y-7.45%Gross Margin0.98%
Operating Margin-0.68%Profit Margin-0.65%
ROE-1.11%ROA-0.19%
ROCE-0.22%Current Ratio7.89
Quick Ratio7.73Cash Ratio1.11
Debt/Equity3.67Interest Coverage-9.48
Altman Z Score1.42Piotroski Score2

Ionis Pharmaceuticals (IONS) valuation & financials

Ionis Pharmaceuticals (IONS) has a market capitalization of $9.01B and trades at a price-to-earnings ratio of -31.5. It operates in the Healthcare sector (Biotechnology).

Ionis Pharmaceuticals's revenue grew -7.4% over the last year.

Ionis Pharmaceuticals's next earnings report is scheduled for November 4, 2026 before market open; analysts estimate EPS of $-1.21. Check the earnings calendar to see all companies reporting this week.

📈 Analysts estimate IONS EPS of $-1.21 for the upcoming quarter. See Ionis Pharmaceuticals revenue & EPS analyst forecasts for the next four quarters with Quarter Chart Premium.

Ionis Pharmaceuticals (IONS) — frequently asked questions

When does Ionis Pharmaceuticals (IONS) report earnings next?

Ionis Pharmaceuticals is expected to report earnings on November 4, 2026 before market open. Analysts estimate EPS of $-1.21.

What is Ionis Pharmaceuticals's market cap?

Ionis Pharmaceuticals (IONS) has a market capitalization of $9.01B.

What is IONS's P/E ratio?

Ionis Pharmaceuticals trades at a price-to-earnings ratio of -31.5, with trailing twelve-month EPS of $-1.72.

How fast is Ionis Pharmaceuticals growing?

Ionis Pharmaceuticals's revenue grew -7.4% over the last year.

Compare with other Healthcare companies: Eli Lilly (LLY) · Johnson & Johnson (JNJ) · AbbVie (ABBV) · Merck (MRK) · UnitedHealth (UNH) · Roche (ROG.SW)